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Simultaneous quantification of acetaminophen and tryptophan using a composite graphene foam/Zr-MOF film modified electrode

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dc.contributor.author Kemmegne-Mbouguen, JC
dc.contributor.author Tchoumi, FP
dc.contributor.author Mouafo-Tchinda, E
dc.contributor.author Langmi, HW
dc.contributor.author Bambalaza, Sonwabo E
dc.contributor.author Musyoka, Nicholas M
dc.contributor.author Kowenje, C
dc.contributor.author Mokaya, R
dc.date.accessioned 2020-11-02T10:57:59Z
dc.date.available 2020-11-02T10:57:59Z
dc.date.issued 2020-07
dc.identifier.citation Kemmegne-Mbouguen, J.C. (et.al.). 2020. Simultaneous quantification of acetaminophen and tryptophan using a composite graphene foam/Zr-MOF film modified electrode. New Journal of Chemistry, v44(30), pp 13108-13117. en_US
dc.identifier.issn 1369-9261
dc.identifier.uri https://pubs.rsc.org/en/content/articlelanding/2020/nj/d0nj02374d#!divAbstract
dc.identifier.uri https://doi.org/10.1039/D0NJ02374D
dc.identifier.uri http://hdl.handle.net/10204/11658
dc.description Copyright: 2020 Royal Society of Chemistry. This is the preprint version of the work. For access to the published version, kindly visit the publisher's website. en_US
dc.description.abstract A graphene foam/zirconium-based metal–organic framework composite (GF/UiO-66) was synthesised and then employed to modify glassy carbon electrodes (GCE). These modified electrodes were successfully used for the simultaneous detection and determination of acetaminophen (AC) and tryptophan (TRYP). The combination of GF and UiO-66 endowed the electrodes with a large surface area, good biological compatibility and stability as well as high selectivity and sensitivity. The linear calibration plots for AC and TRYP were obtained over the range of 0.5–200 µM (R2 = 0.999) and 0.5–113 µM (R2 = 0.999) with detection limits of 0.07 µM and 0.06 µM, respectively. The modified electrodes were successfully applied for the determination of AC and TRYP in a pharmaceutical preparation and urine, respectively. en_US
dc.language.iso en en_US
dc.publisher Royal Society of Chemistry en_US
dc.relation.ispartofseries Worklist;23853
dc.subject Graphene foam en_US
dc.subject UiO-66 en_US
dc.subject Modified electrodes en_US
dc.subject Electroanalysis en_US
dc.subject Acetaminophen en_US
dc.subject Tryptophan en_US
dc.title Simultaneous quantification of acetaminophen and tryptophan using a composite graphene foam/Zr-MOF film modified electrode en_US
dc.type Article en_US
dc.identifier.apacitation Kemmegne-Mbouguen, J., Tchoumi, F., Mouafo-Tchinda, E., Langmi, H., Bambalaza, S. E., Musyoka, N. M., ... Mokaya, R. (2020). Simultaneous quantification of acetaminophen and tryptophan using a composite graphene foam/Zr-MOF film modified electrode. http://hdl.handle.net/10204/11658 en_ZA
dc.identifier.chicagocitation Kemmegne-Mbouguen, JC, FP Tchoumi, E Mouafo-Tchinda, HW Langmi, Sonwabo E Bambalaza, Nicholas M Musyoka, C Kowenje, and R Mokaya "Simultaneous quantification of acetaminophen and tryptophan using a composite graphene foam/Zr-MOF film modified electrode." (2020) http://hdl.handle.net/10204/11658 en_ZA
dc.identifier.vancouvercitation Kemmegne-Mbouguen J, Tchoumi F, Mouafo-Tchinda E, Langmi H, Bambalaza SE, Musyoka NM, et al. Simultaneous quantification of acetaminophen and tryptophan using a composite graphene foam/Zr-MOF film modified electrode. 2020; http://hdl.handle.net/10204/11658. en_ZA
dc.identifier.ris TY - Article AU - Kemmegne-Mbouguen, JC AU - Tchoumi, FP AU - Mouafo-Tchinda, E AU - Langmi, HW AU - Bambalaza, Sonwabo E AU - Musyoka, Nicholas M AU - Kowenje, C AU - Mokaya, R AB - A graphene foam/zirconium-based metal–organic framework composite (GF/UiO-66) was synthesised and then employed to modify glassy carbon electrodes (GCE). These modified electrodes were successfully used for the simultaneous detection and determination of acetaminophen (AC) and tryptophan (TRYP). The combination of GF and UiO-66 endowed the electrodes with a large surface area, good biological compatibility and stability as well as high selectivity and sensitivity. The linear calibration plots for AC and TRYP were obtained over the range of 0.5–200 µM (R2 = 0.999) and 0.5–113 µM (R2 = 0.999) with detection limits of 0.07 µM and 0.06 µM, respectively. The modified electrodes were successfully applied for the determination of AC and TRYP in a pharmaceutical preparation and urine, respectively. DA - 2020-07 DB - ResearchSpace DP - CSIR KW - Graphene foam KW - UiO-66 KW - Modified electrodes KW - Electroanalysis KW - Acetaminophen KW - Tryptophan LK - https://researchspace.csir.co.za PY - 2020 SM - 1369-9261 T1 - Simultaneous quantification of acetaminophen and tryptophan using a composite graphene foam/Zr-MOF film modified electrode TI - Simultaneous quantification of acetaminophen and tryptophan using a composite graphene foam/Zr-MOF film modified electrode UR - http://hdl.handle.net/10204/11658 ER - en_ZA


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