dc.contributor.author |
Mabank, T
|
|
dc.contributor.author |
Alexandre, Kabamba B
|
|
dc.contributor.author |
Pelly, SC
|
|
dc.contributor.author |
Green, IR
|
|
dc.contributor.author |
Van Otterlo, WAL
|
|
dc.date.accessioned |
2020-02-27T10:35:56Z |
|
dc.date.available |
2020-02-27T10:35:56Z |
|
dc.date.issued |
2019-07 |
|
dc.identifier.citation |
Mabank, T., Alexandre, K.B., Pelly, S.C., Green, I.R. and Van Otterlo, W.A.L. 2019. Synthesis of 2-substituted tetrahydroisoquinolin-6-ols: Potential scaffolds for estrogen receptor modulation and/or microtubule degradation. ARKIVOC, July 2019, Part 4, pp 245-279. |
en_US |
dc.identifier.issn |
1551-7012 |
|
dc.identifier.uri |
https://www.arkat-usa.org/get-file/67071/
|
|
dc.identifier.uri |
https://www.arkat-usa.org/arkivoc-journal/browse-arkivoc/ark.5550190.p010.962
|
|
dc.identifier.uri |
http://hdl.handle.net/10204/11303
|
|
dc.description |
Copyright: 2019 ARKAT USA INC. Content is disseminated under a Creative Commons Attribution License (CC BY) |
en_US |
dc.description.abstract |
6-Methoxytetrahydroisoquinoline hydrochloride was converted into four small libraries of substituted ureas, thioureas, sulfonamides and N-aryls, using the tetrahydroisoquinoline nitrogen as the scaffold-linking atom. Some of the compounds were evaluated for their ability to inhibit cell proliferation using the MCF7 (invasive ductal carcinoma) cell line. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
ARKAT USA INC |
en_US |
dc.relation.ispartofseries |
Worklist;22668 |
|
dc.subject |
6-Hydroxytetrahydroisoquinolines |
en_US |
dc.subject |
Anti-cancer |
en_US |
dc.subject |
Estrogen modulators |
en_US |
dc.subject |
Sulfonamides |
en_US |
dc.subject |
Thioureas |
en_US |
dc.subject |
Ureas |
en_US |
dc.title |
Synthesis of 2-substituted tetrahydroisoquinolin-6-ols: Potential scaffolds for estrogen receptor modulation and/or microtubule degradation |
en_US |
dc.type |
Article |
en_US |
dc.identifier.apacitation |
Mabank, T., Alexandre, K. B., Pelly, S., Green, I., & Van Otterlo, W. (2019). Synthesis of 2-substituted tetrahydroisoquinolin-6-ols: Potential scaffolds for estrogen receptor modulation and/or microtubule degradation. http://hdl.handle.net/10204/11303 |
en_ZA |
dc.identifier.chicagocitation |
Mabank, T, Kabamba B Alexandre, SC Pelly, IR Green, and WAL Van Otterlo "Synthesis of 2-substituted tetrahydroisoquinolin-6-ols: Potential scaffolds for estrogen receptor modulation and/or microtubule degradation." (2019) http://hdl.handle.net/10204/11303 |
en_ZA |
dc.identifier.vancouvercitation |
Mabank T, Alexandre KB, Pelly S, Green I, Van Otterlo W. Synthesis of 2-substituted tetrahydroisoquinolin-6-ols: Potential scaffolds for estrogen receptor modulation and/or microtubule degradation. 2019; http://hdl.handle.net/10204/11303. |
en_ZA |
dc.identifier.ris |
TY - Article
AU - Mabank, T
AU - Alexandre, Kabamba B
AU - Pelly, SC
AU - Green, IR
AU - Van Otterlo, WAL
AB - 6-Methoxytetrahydroisoquinoline hydrochloride was converted into four small libraries of substituted ureas, thioureas, sulfonamides and N-aryls, using the tetrahydroisoquinoline nitrogen as the scaffold-linking atom. Some of the compounds were evaluated for their ability to inhibit cell proliferation using the MCF7 (invasive ductal carcinoma) cell line.
DA - 2019-07
DB - ResearchSpace
DP - CSIR
KW - 6-Hydroxytetrahydroisoquinolines
KW - Anti-cancer
KW - Estrogen modulators
KW - Sulfonamides
KW - Thioureas
KW - Ureas
LK - https://researchspace.csir.co.za
PY - 2019
SM - 1551-7012
T1 - Synthesis of 2-substituted tetrahydroisoquinolin-6-ols: Potential scaffolds for estrogen receptor modulation and/or microtubule degradation
TI - Synthesis of 2-substituted tetrahydroisoquinolin-6-ols: Potential scaffolds for estrogen receptor modulation and/or microtubule degradation
UR - http://hdl.handle.net/10204/11303
ER -
|
en_ZA |