dc.contributor.author |
Sakong, BM
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|
dc.contributor.author |
Adenubi, OT
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|
dc.contributor.author |
Pauw, E
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|
dc.contributor.author |
Eloff, JN
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|
dc.contributor.author |
Fouché, Gerda
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|
dc.contributor.author |
Leboho, Tlabo
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dc.contributor.author |
Wellington, Kevin W
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|
dc.date.accessioned |
2017-06-07T07:14:03Z |
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dc.date.available |
2017-06-07T07:14:03Z |
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dc.date.issued |
2016 |
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dc.identifier.citation |
Fouche, G., Sakong, B.M., Adenubi, O.T. et al. 2016. Anthelmintic activity of acetone extracts from South African plants used on egg hatching of Haemonchus contortus. Onderstepoort Journal of Veterinary Research, vol. 83(1): doi.org/10.4102/ojvr.v83i1.1164 |
en_US |
dc.identifier.issn |
0030-2465 |
|
dc.identifier.uri |
http://journals.co.za/content/opvet/83/1/EJC196363
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|
dc.identifier.uri |
doi.org/10.4102/ojvr.v83i1.1164
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|
dc.identifier.uri |
http://hdl.handle.net/10204/9194
|
|
dc.description |
Copyright: © 2016. The Authors. Licensee: AOSIS. This work is licensed under the
Creative Commons Attribution License. |
en_US |
dc.description.abstract |
The nematode, Haemonchus contortus, is responsible for major economic losses in the livestock industry. The management of parasites such as H. contortus has been through the use of synthetic parasiticides. This has resulted in the presence of residues in meat and milk, which affects food safety. The development of resistance to available anthelmintics coupled with their high cost has further complicated matters. This has led to the investigation of alternative methods to manage nematodes, including the use of plants and plant extracts as a potential source of novel anthelmintics. Acetone extracts were prepared from 15 South African plant species and their anthelmintic activity determined using the egg hatch assay (EHA). The leaf extract of Cleome gynandra had the best inhibitory activity (68% ± 3%) at a concentration of 2.5 mg/mL, followed by the stem extract of Maerua angolensis (65% ± 5%). The extracts had a relatively low toxicity on Vero cells determined by the MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) cellular assay. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
AOSIS |
en_US |
dc.relation.ispartofseries |
Worklist;18085 |
|
dc.subject |
Livestock production |
en_US |
dc.subject |
Gastrointestinal parasites |
en_US |
dc.subject |
Haemonchus contortus |
en_US |
dc.subject |
South African plants |
en_US |
dc.subject |
Livestock diseases |
en_US |
dc.title |
Anthelmintic activity of acetone extracts from South African plants used on egg hatching of Haemonchus contortus |
en_US |
dc.type |
Article |
en_US |
dc.identifier.apacitation |
Sakong, B., Adenubi, O., Pauw, E., Eloff, J., Fouché, G., Leboho, T., & Wellington, K. W. (2016). Anthelmintic activity of acetone extracts from South African plants used on egg hatching of Haemonchus contortus. http://hdl.handle.net/10204/9194 |
en_ZA |
dc.identifier.chicagocitation |
Sakong, BM, OT Adenubi, E Pauw, JN Eloff, Gerda Fouché, Tlabo Leboho, and Kevin W Wellington "Anthelmintic activity of acetone extracts from South African plants used on egg hatching of Haemonchus contortus." (2016) http://hdl.handle.net/10204/9194 |
en_ZA |
dc.identifier.vancouvercitation |
Sakong B, Adenubi O, Pauw E, Eloff J, Fouché G, Leboho T, et al. Anthelmintic activity of acetone extracts from South African plants used on egg hatching of Haemonchus contortus. 2016; http://hdl.handle.net/10204/9194. |
en_ZA |
dc.identifier.ris |
TY - Article
AU - Sakong, BM
AU - Adenubi, OT
AU - Pauw, E
AU - Eloff, JN
AU - Fouché, Gerda
AU - Leboho, Tlabo
AU - Wellington, Kevin W
AB - The nematode, Haemonchus contortus, is responsible for major economic losses in the livestock industry. The management of parasites such as H. contortus has been through the use of synthetic parasiticides. This has resulted in the presence of residues in meat and milk, which affects food safety. The development of resistance to available anthelmintics coupled with their high cost has further complicated matters. This has led to the investigation of alternative methods to manage nematodes, including the use of plants and plant extracts as a potential source of novel anthelmintics. Acetone extracts were prepared from 15 South African plant species and their anthelmintic activity determined using the egg hatch assay (EHA). The leaf extract of Cleome gynandra had the best inhibitory activity (68% ± 3%) at a concentration of 2.5 mg/mL, followed by the stem extract of Maerua angolensis (65% ± 5%). The extracts had a relatively low toxicity on Vero cells determined by the MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) cellular assay.
DA - 2016
DB - ResearchSpace
DP - CSIR
KW - Livestock production
KW - Gastrointestinal parasites
KW - Haemonchus contortus
KW - South African plants
KW - Livestock diseases
LK - https://researchspace.csir.co.za
PY - 2016
SM - 0030-2465
T1 - Anthelmintic activity of acetone extracts from South African plants used on egg hatching of Haemonchus contortus
TI - Anthelmintic activity of acetone extracts from South African plants used on egg hatching of Haemonchus contortus
UR - http://hdl.handle.net/10204/9194
ER -
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en_ZA |