Strong, bioinert materials have always been the focus for bone replacement and repair. This practice has since moved towards materials that can mimic living tissue and aid the healing process (i.e. be replaced by natural bone); thus materials that are bioactive as well as bioresorbable1, 2. Currently, the most widely used bioactive bone substitute is calcium phosphate-based materials. However, these calcium phosphate-based materials (i.e. hydroxyapatite (HA) and β-tricalcium phosphate (TC P)) do not fulfil all the current requirements for bone repair and replacement due to some characteristics such as Lack of collagen fibres
Reference:
Wepnener, I, Richter, W and Joubert, A. 2010. Nano-calciumphosphate scaffold generation for bone repair/replacement: elucidating the signalling response and cell cycle. CSIR 3rd Biennial Conference 2010. Science Real and Relevant. CSIR International Convention Centre, Pretoria, South Africa, 30 August – 01 September 2010, pp 1
Wepnener, I., Richter, W., & Joubert, A. (2010). Nano-calciumphosphate scaffold generation for bone repair/replacement: elucidating the signalling response and cell cycle. CSIR. http://hdl.handle.net/10204/4326
Wepnener, I, W Richter, and A Joubert. "Nano-calciumphosphate scaffold generation for bone repair/replacement: elucidating the signalling response and cell cycle." (2010): http://hdl.handle.net/10204/4326
Wepnener I, Richter W, Joubert A, Nano-calciumphosphate scaffold generation for bone repair/replacement: elucidating the signalling response and cell cycle; CSIR; 2010. http://hdl.handle.net/10204/4326 .
CSIR 3rd Biennial Conference 2010. Science Real and Relevant. CSIR International Convention Centre, Pretoria, South Africa, 30 August – 01 September 2010