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Metallophthalocyanine based carbon paste electrodes for the determination of 2’,3’-Dideoxyinosine

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dc.contributor.author Ozoemena, KI
dc.contributor.author Stefan-van Staden, RI
dc.contributor.author Nyokong, T
dc.date.accessioned 2009-09-15T11:50:36Z
dc.date.available 2009-09-15T11:50:36Z
dc.date.issued 2009-07
dc.identifier.citation Ozoemena, KI, Stefan-van Staden, RI and Nyokong, T. 2009. Metallophthalocyanine based carbon paste electrodes for the determination of 2’,3’-Dideoxyinosine. Electroanalysis, Vol. 21(14). pp 1651- 1654 en
dc.identifier.issn 1040-0397
dc.identifier.uri http://hdl.handle.net/10204/3589
dc.description Copyright: 2009 Wiley-VCH Verlag. This is the author's version of the work. It is posted here by permission of Wiley-VCH Verlag for your personal use. Not for redistribution. The definitive version was published in the journal, Electroanalysis, Vol. 21(14). pp 1651- 1654 en
dc.description.abstract Novel electrochemical sensors based on carbon paste impregnated with metallopthalocyanine (MPc, M¼Co, Fe) complexes, have been constructed for the assay of anti-HIV drug 2’,3’-dideoxyinosine (didanosine, DDI). Both modified electrodes showed electrocatalytic activity towards the oxidation of dideoxyinosine in phosphate buffer pH 7.4 with a working concentration range of 10-6–10-4 mol/L and a detection limit of 10-7 mol/L magnitude order. The sensor proved to be highly reliable for the assay of the purity of DDI - raw material as well as for the uniformity content test of Videx tablets. en
dc.language.iso en en
dc.publisher Wiley-VCH Verlag en
dc.subject Metallophthalocyanine en
dc.subject 2',3'-Dideoxyinosine en
dc.subject Differential pulse voltammetry en
dc.subject Novel electrochemical sensors en
dc.subject Drug design en
dc.subject Cobalt(II) en
dc.subject Iron(II) phthalocyanines en
dc.subject Electroanalysis en
dc.subject Carbon paste electrodes en
dc.title Metallophthalocyanine based carbon paste electrodes for the determination of 2’,3’-Dideoxyinosine en
dc.type Article en
dc.identifier.apacitation Ozoemena, K., Stefan-van Staden, R., & Nyokong, T. (2009). Metallophthalocyanine based carbon paste electrodes for the determination of 2’,3’-Dideoxyinosine. http://hdl.handle.net/10204/3589 en_ZA
dc.identifier.chicagocitation Ozoemena, KI, RI Stefan-van Staden, and T Nyokong "Metallophthalocyanine based carbon paste electrodes for the determination of 2’,3’-Dideoxyinosine." (2009) http://hdl.handle.net/10204/3589 en_ZA
dc.identifier.vancouvercitation Ozoemena K, Stefan-van Staden R, Nyokong T. Metallophthalocyanine based carbon paste electrodes for the determination of 2’,3’-Dideoxyinosine. 2009; http://hdl.handle.net/10204/3589. en_ZA
dc.identifier.ris TY - Article AU - Ozoemena, KI AU - Stefan-van Staden, RI AU - Nyokong, T AB - Novel electrochemical sensors based on carbon paste impregnated with metallopthalocyanine (MPc, M¼Co, Fe) complexes, have been constructed for the assay of anti-HIV drug 2’,3’-dideoxyinosine (didanosine, DDI). Both modified electrodes showed electrocatalytic activity towards the oxidation of dideoxyinosine in phosphate buffer pH 7.4 with a working concentration range of 10-6–10-4 mol/L and a detection limit of 10-7 mol/L magnitude order. The sensor proved to be highly reliable for the assay of the purity of DDI - raw material as well as for the uniformity content test of Videx tablets. DA - 2009-07 DB - ResearchSpace DP - CSIR KW - Metallophthalocyanine KW - 2',3'-Dideoxyinosine KW - Differential pulse voltammetry KW - Novel electrochemical sensors KW - Drug design KW - Cobalt(II) KW - Iron(II) phthalocyanines KW - Electroanalysis KW - Carbon paste electrodes LK - https://researchspace.csir.co.za PY - 2009 SM - 1040-0397 T1 - Metallophthalocyanine based carbon paste electrodes for the determination of 2’,3’-Dideoxyinosine TI - Metallophthalocyanine based carbon paste electrodes for the determination of 2’,3’-Dideoxyinosine UR - http://hdl.handle.net/10204/3589 ER - en_ZA


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