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Effect of substituent structure on pyrimidine electrophilic substitution

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dc.contributor.author Van der Westhuyzen, Christiaan W
dc.contributor.author Rousseau, AL
dc.contributor.author Parkinson, CJ
dc.date.accessioned 2007-10-23T14:00:24Z
dc.date.available 2007-10-23T14:00:24Z
dc.date.issued 2007
dc.identifier.citation Van der Westhuyzen, CW, Rousseau, AL and Parkinson, CJ. 2007. Effect of substituent structure on pyrimidine electrophilic substitution. Tetrahedron -London, Vol. 63, pp 5394-5405 en
dc.identifier.issn 0040-4020
dc.identifier.uri http://hdl.handle.net/10204/1370
dc.description Copyright: 2007 Elsevier Science B.V en
dc.description.abstract In an investigation into the electrophilic nitrosation reactions of a series of 4,6-disubstituted pyrimidine derivatives, a subtle interplay between the electronic nature of the C-4 and C-6 substituents and reactivity was found where these were chloro-, mono- or disubstituted amino groups. Effects such as the presence of an aryl group or two alkyl groups on the amino moiety impede the progress of the reaction despite the presence of a second activating group. en
dc.language.iso en en
dc.publisher Elsevier Science B.V en
dc.subject Pyrimidine en
dc.subject Electrophilic nitrosation en
dc.subject Amino groups en
dc.subject Aryl group en
dc.subject Alkyl group en
dc.title Effect of substituent structure on pyrimidine electrophilic substitution en
dc.type Article en
dc.identifier.apacitation Van der Westhuyzen, C. W., Rousseau, A., & Parkinson, C. (2007). Effect of substituent structure on pyrimidine electrophilic substitution. http://hdl.handle.net/10204/1370 en_ZA
dc.identifier.chicagocitation Van der Westhuyzen, Christiaan W, AL Rousseau, and CJ Parkinson "Effect of substituent structure on pyrimidine electrophilic substitution." (2007) http://hdl.handle.net/10204/1370 en_ZA
dc.identifier.vancouvercitation Van der Westhuyzen CW, Rousseau A, Parkinson C. Effect of substituent structure on pyrimidine electrophilic substitution. 2007; http://hdl.handle.net/10204/1370. en_ZA
dc.identifier.ris TY - Article AU - Van der Westhuyzen, Christiaan W AU - Rousseau, AL AU - Parkinson, CJ AB - In an investigation into the electrophilic nitrosation reactions of a series of 4,6-disubstituted pyrimidine derivatives, a subtle interplay between the electronic nature of the C-4 and C-6 substituents and reactivity was found where these were chloro-, mono- or disubstituted amino groups. Effects such as the presence of an aryl group or two alkyl groups on the amino moiety impede the progress of the reaction despite the presence of a second activating group. DA - 2007 DB - ResearchSpace DP - CSIR KW - Pyrimidine KW - Electrophilic nitrosation KW - Amino groups KW - Aryl group KW - Alkyl group LK - https://researchspace.csir.co.za PY - 2007 SM - 0040-4020 T1 - Effect of substituent structure on pyrimidine electrophilic substitution TI - Effect of substituent structure on pyrimidine electrophilic substitution UR - http://hdl.handle.net/10204/1370 ER - en_ZA


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