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Layered double hydroxides: An advanced encapsulation and delivery system for cosmetic ingredients-an overview

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dc.contributor.author Kesavan Pillai, Sreejarani
dc.contributor.author Kleyi, Phumelele E
dc.contributor.author De Beer, Marinda
dc.contributor.author Mudaly, Preensha
dc.date.accessioned 2021-04-05T19:55:53Z
dc.date.available 2021-04-05T19:55:53Z
dc.date.issued 2020-12
dc.identifier.citation Kesavan Pillai, S., Kleyi, P.E., De Beer, M. & Mudaly, P. 2020. Layered double hydroxides: An advanced encapsulation and delivery system for cosmetic ingredients-an overview. <i>Applied Clay Science, 199.</i> http://hdl.handle.net/10204/11934 en_ZA
dc.identifier.issn 0169-1317
dc.identifier.issn 1872-9053
dc.identifier.uri http://hdl.handle.net/10204/11934
dc.description.abstract Topical delivery of active ingredients is very challenging because of the complex structure and excellent barrier properties of human skin. Advances in nanotechnology resulted in nanomaterial based delivery systems to augment the skin absorption of hydrophilic, hydrophobic and high molecular weight molecules. Nanostructured layered double hydroxides (LDH), owing to its exceptional features; such as large surface area, expandable interlayer space to accommodate active molecules, biocompatibility, high water holding efficiency, rheological and swelling properties, as well as cost effectiveness, have been proposed as innovative carriers of active ingredients for its effective transfer through skin. This is achieved by altering the active molecule release profiles, improving the stability of the active, increasing the solubility and bioavailability. This article intends to give an outline of recent research efforts in the development pertaining LDH based advanced skin delivery systems for cosmetic ingredients, the associated challenges and future perspectives. Special consideration is dedicated to the functionalities of LDH and its prospects in controlled release for cosmetic ingredients. The examples and discussions illustrating the application of LDH in topical delivery are centered around UV protection, skin care and antimicrobial properties. en_US
dc.format Abstract en_US
dc.language.iso en en_US
dc.relation.uri https://doi.org/10.1016/j.clay.2020.105868 en_US
dc.relation.uri https://www.sciencedirect.com/science/article/pii/S0169131720304336 en_US
dc.source Applied Clay Science, 199 en_US
dc.subject Active ingredients en_US
dc.subject Cosmetics en_US
dc.subject Delivery systems en_US
dc.subject Layered double hydroxides en_US
dc.title Layered double hydroxides: An advanced encapsulation and delivery system for cosmetic ingredients-an overview en_US
dc.type Article en_US
dc.description.pages 12pp en_US
dc.description.note © 2020 Elsevier B.V. All rights reserved. Due to copyright restrictions, the attached PDF file contains the abstract of the full-text item. For access to the full-text item, please consult the publisher's website: https://www.sciencedirect.com/science/article/abs/pii/S0169131720304336 en_US
dc.description.cluster Chemicals en_US
dc.description.impactarea Advanced Functional Materials en_US
dc.identifier.apacitation Kesavan Pillai, S., Kleyi, P. E., De Beer, M., & Mudaly, P. (2020). Layered double hydroxides: An advanced encapsulation and delivery system for cosmetic ingredients-an overview. <i>Applied Clay Science, 199</i>, http://hdl.handle.net/10204/11934 en_ZA
dc.identifier.chicagocitation Kesavan Pillai, Sreejarani, Phumelele E Kleyi, Marinda De Beer, and Preensha Mudaly "Layered double hydroxides: An advanced encapsulation and delivery system for cosmetic ingredients-an overview." <i>Applied Clay Science, 199</i> (2020) http://hdl.handle.net/10204/11934 en_ZA
dc.identifier.vancouvercitation Kesavan Pillai S, Kleyi PE, De Beer M, Mudaly P. Layered double hydroxides: An advanced encapsulation and delivery system for cosmetic ingredients-an overview. Applied Clay Science, 199. 2020; http://hdl.handle.net/10204/11934. en_ZA
dc.identifier.ris TY - Article AU - Kesavan Pillai, Sreejarani AU - Kleyi, Phumelele E AU - De Beer, Marinda AU - Mudaly, Preensha AB - Topical delivery of active ingredients is very challenging because of the complex structure and excellent barrier properties of human skin. Advances in nanotechnology resulted in nanomaterial based delivery systems to augment the skin absorption of hydrophilic, hydrophobic and high molecular weight molecules. Nanostructured layered double hydroxides (LDH), owing to its exceptional features; such as large surface area, expandable interlayer space to accommodate active molecules, biocompatibility, high water holding efficiency, rheological and swelling properties, as well as cost effectiveness, have been proposed as innovative carriers of active ingredients for its effective transfer through skin. This is achieved by altering the active molecule release profiles, improving the stability of the active, increasing the solubility and bioavailability. This article intends to give an outline of recent research efforts in the development pertaining LDH based advanced skin delivery systems for cosmetic ingredients, the associated challenges and future perspectives. Special consideration is dedicated to the functionalities of LDH and its prospects in controlled release for cosmetic ingredients. The examples and discussions illustrating the application of LDH in topical delivery are centered around UV protection, skin care and antimicrobial properties. DA - 2020-12 DB - ResearchSpace DP - CSIR J1 - Applied Clay Science, 199 KW - Active ingredients KW - Cosmetics KW - Delivery systems KW - Layered double hydroxides LK - https://researchspace.csir.co.za PY - 2020 SM - 0169-1317 SM - 1872-9053 T1 - Layered double hydroxides: An advanced encapsulation and delivery system for cosmetic ingredients-an overview TI - Layered double hydroxides: An advanced encapsulation and delivery system for cosmetic ingredients-an overview UR - http://hdl.handle.net/10204/11934 ER - en_ZA
dc.identifier.worklist 24047 en_US


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