Author:Katata, L; Tshweu, L; Naidoo, Saloshnee; Kalombo, Lonji; Swai, HDate:Oct 2012Efavirenz (EFV) is one of the first-line antiretroviral drugs recommended by the World Health Organisation for treating HIV. It is a hydrophobic drug that suffers from low aqueous solubility (4 lg/mL), which leads to a limited oral absorption ...Read more
Author:Labuschagne, Philip W; Adami, R; Liparoti, S; Naidoo, Saloshnee; Swai, H; Reverchon, EDate:Nov 2014In this work supercritical assisted atomization (SAA) process was used for the co-precipitation of poly(d,l-lactide) (PDLLA) and rifampicin (RIF) as nanoparticles for sustained release applications. The effect of the variation of PDLLA/RIF ...Read more