dc.contributor.author |
Riley, DL
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|
dc.contributor.author |
Strydom, I
|
|
dc.contributor.author |
Chikwamba, Rachel K
|
|
dc.contributor.author |
Panayides, Jenny-Lee
|
|
dc.date.accessioned |
2020-04-11T11:42:31Z |
|
dc.date.available |
2020-04-11T11:42:31Z |
|
dc.date.issued |
2019 |
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dc.identifier.citation |
Riley, D.L. et al. 2019. Landscape and opportunities for active pharmaceutical ingredient manufacturing in developing African economies. Reaction Chemistry & Engineering, vol. 4: 457-489 |
en_US |
dc.identifier.issn |
2058-9883 |
|
dc.identifier.uri |
https://pubs.rsc.org/en/content/articlelanding/2019/re/c8re00236c#!divAbstract
|
|
dc.identifier.uri |
https://doi.org/10.1039/C8RE00236C
|
|
dc.identifier.uri |
http://hdl.handle.net/10204/11403
|
|
dc.description |
Copyright: 2019 RSC. Due to copyright restrictions, the attached PDF file only contains the abstract of the full text item. For access to the full text item, please consult the publisher's website. The definitive version of the work is published at https://doi.org/10.1039/C8RE00236C |
en_US |
dc.description.abstract |
Africa is one of the world's fastest growing economies, with South Africa having the fifth highest worldwide pharmaceutical expenditure per capita. In recent years, several companies have considered regional pharmaceutical production but have failed to make the investment, in stark contrast to the massive growth in pharmaceutical production in other BRICS countries. Major constraints identified have been the small local market, lack of skills, and an export-averse culture, which have prevented regional manufacturers from achieving the economies of scale that are essential to survive in a global market. In contrast, the pharmaceutical industry is undergoing a revolutionary change in manufacturing, with the potential to switch from batch manufacturing to continuous flow processing. The possibility of applying this new pharmaceutical business model in emerging markets will open the door for dramatic changes in regional commercial manufacturing. Advances in cloud computing, automation and system unification are paving the way for continuous active pharmaceutical ingredient production with integrated digital connectivity. This review will highlight the opportunities that exist in the localization of cutting-edge manufacturing technologies; in order to show the potential application of fundamental process research key production examples relevant to the region will be provided. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
Royal Society of Chemistry |
en_US |
dc.relation.ispartofseries |
Worklist;23431 |
|
dc.subject |
BRICS pharmaceutical production |
en_US |
dc.subject |
Pharmaceutical ingredient manufacturing |
en_US |
dc.title |
Landscape and opportunities for active pharmaceutical ingredient manufacturing in developing African economies |
en_US |
dc.type |
Article |
en_US |
dc.identifier.apacitation |
Riley, D., Strydom, I., Chikwamba, R. K., & Panayides, J. (2019). Landscape and opportunities for active pharmaceutical ingredient manufacturing in developing African economies. http://hdl.handle.net/10204/11403 |
en_ZA |
dc.identifier.chicagocitation |
Riley, DL, I Strydom, Rachel K Chikwamba, and Jenny-Lee Panayides "Landscape and opportunities for active pharmaceutical ingredient manufacturing in developing African economies." (2019) http://hdl.handle.net/10204/11403 |
en_ZA |
dc.identifier.vancouvercitation |
Riley D, Strydom I, Chikwamba RK, Panayides J. Landscape and opportunities for active pharmaceutical ingredient manufacturing in developing African economies. 2019; http://hdl.handle.net/10204/11403. |
en_ZA |
dc.identifier.ris |
TY - Article
AU - Riley, DL
AU - Strydom, I
AU - Chikwamba, Rachel K
AU - Panayides, Jenny-Lee
AB - Africa is one of the world's fastest growing economies, with South Africa having the fifth highest worldwide pharmaceutical expenditure per capita. In recent years, several companies have considered regional pharmaceutical production but have failed to make the investment, in stark contrast to the massive growth in pharmaceutical production in other BRICS countries. Major constraints identified have been the small local market, lack of skills, and an export-averse culture, which have prevented regional manufacturers from achieving the economies of scale that are essential to survive in a global market. In contrast, the pharmaceutical industry is undergoing a revolutionary change in manufacturing, with the potential to switch from batch manufacturing to continuous flow processing. The possibility of applying this new pharmaceutical business model in emerging markets will open the door for dramatic changes in regional commercial manufacturing. Advances in cloud computing, automation and system unification are paving the way for continuous active pharmaceutical ingredient production with integrated digital connectivity. This review will highlight the opportunities that exist in the localization of cutting-edge manufacturing technologies; in order to show the potential application of fundamental process research key production examples relevant to the region will be provided.
DA - 2019
DB - ResearchSpace
DP - CSIR
KW - BRICS pharmaceutical production
KW - Pharmaceutical ingredient manufacturing
LK - https://researchspace.csir.co.za
PY - 2019
SM - 2058-9883
T1 - Landscape and opportunities for active pharmaceutical ingredient manufacturing in developing African economies
TI - Landscape and opportunities for active pharmaceutical ingredient manufacturing in developing African economies
UR - http://hdl.handle.net/10204/11403
ER -
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en_ZA |