Herbs and plant extracts are very popular and are being used by all cultures for healthcare and as food supplements. The correct identification of the required plant material is vital for formulation of final formulas for use by mankind. The use of instruments such as UPLC-QTOF-MS can be advantageous in the identification and authentication of plant extracts and formulated products to ensure the safe use of these products. Furthermore, it is also imperative that the extracts are not contaminated with other chemicals or pesticides as this can be detrimental to humans during the consumption of these products. Organic extracts of six example plants were made as part of the PlantLIBRA collaboration. The development of UPLC-QTOF-MS profiling methods showed that separation of the major compounds found in the extracts was possible and allowed for high resolution mass spectral evaluation of the compounds detected. By using reference standards and published literature, the presence of active or marker compounds could be confirmed in the different plant extracts. The high mass accuracy of the TOF data also allowed for the tentative identification of extra compounds as well as the ability to differentiate between different formulations. Establishing the correct chemical profile of a plant before use as a food supplement or herbal formulation, would ensure the use of the correct plant species, but also detect any new compounds or contaminants such as pesticides or toxins which may be identified using UPLC- QTOF-MS technologies.
Reference:
Steenkamp, P.A., Steenkamp, L.H. and Mancama, D.T. 2018. Profiling of botanical extracts for authentication, detection of adulteration and quality control using UPLC-QTOF-MS. Food Supplements Containing Botanicals: Benefits, Side Effects and Regulatory Aspects, pp 303-347.
Steenkamp, P. A., Steenkamp, L. H., & Mancama, D. T. (2018). Profiling of botanical extracts for authentication, detection of adulteration and quality control using UPLC-QTOF-MS., Worklist;21264 Springer. http://hdl.handle.net/10204/10744
Steenkamp, Paul A, Lucia H Steenkamp, and Dalubuhle T Mancama. "Profiling of botanical extracts for authentication, detection of adulteration and quality control using UPLC-QTOF-MS" In WORKLIST;21264, n.p.: Springer. 2018. http://hdl.handle.net/10204/10744.
Steenkamp PA, Steenkamp LH, Mancama DT. Profiling of botanical extracts for authentication, detection of adulteration and quality control using UPLC-QTOF-MS.. Worklist;21264. [place unknown]: Springer; 2018. [cited yyyy month dd]. http://hdl.handle.net/10204/10744.
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