dc.contributor.author |
Saasa, Valentine R
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|
dc.contributor.author |
Malwela, Thomas
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|
dc.contributor.author |
Beukes, M
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|
dc.contributor.author |
Mokgotho, M
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dc.contributor.author |
Liu, CP
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dc.contributor.author |
Mwakikunga, Bonex W
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dc.date.accessioned |
2018-12-11T08:51:30Z |
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dc.date.available |
2018-12-11T08:51:30Z |
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dc.date.issued |
2018-01 |
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dc.identifier.citation |
Saasa, V.R. et al. 2018. Sensing technologies for detection of acetone in human breath for diabetes diagnosis and monitoring. Diagnostics, vol. 8(1): 17pp |
en_US |
dc.identifier.issn |
2075-4418 |
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dc.identifier.uri |
https://www.mdpi.com/2075-4418/8/1/12
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dc.identifier.uri |
https://doi.org/10.3390/diagnostics8010012
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dc.identifier.uri |
http://hdl.handle.net/10204/10591
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dc.description |
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0). |
en_US |
dc.description.abstract |
The review describes the technologies used in the field of breath analysis to diagnose and monitor diabetes mellitus. Currently the diagnosis and monitoring of blood glucose and ketone bodies that are used in clinical studies involve the use of blood tests. This method entails pricking fingers for a drop of blood and placing a drop on a sensitive area of a strip which is pre-inserted into an electronic reading instrument. Furthermore, it is painful, invasive and expensive, and can be unsafe if proper handling is not undertaken. Human breath analysis offers a non-invasive and rapid method for detecting various volatile organic compounds thatare indicators for different diseases. In patients with diabetes mellitus, the body produces excess amounts of ketones such as acetoacetate, beta-hydroxybutyrate and acetone. Acetone is exhaled during respiration. The production of acetone is a result of the body metabolising fats instead of glucose to produce energy. There are various techniques that are used to analyse exhaled breath including Gas Chromatography Mass Spectrometry (GC-MS), Proton Transfer Reaction Mass Spectrometry (PTR-MS), Selected Ion Flow Tube-Mass Spectrometry (SIFT-MS), laser photoacoustic spectrometry and so on. All these techniques are not portable, therefore this review places emphasis on how nanotechnology, through semiconductor sensing nanomaterials, has the potential to help individuals living with diabetes mellitus monitor their disease with cheap and portable devices. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
MDPI |
en_US |
dc.relation.ispartofseries |
Worklist;21388 |
|
dc.subject |
Acetone detection |
en_US |
dc.subject |
Breath analysis |
en_US |
dc.subject |
Chemoresistive sensors |
en_US |
dc.subject |
Diabetes mellitus |
en_US |
dc.subject |
Nanomaterials |
en_US |
dc.subject |
Non-invasive diagnosis |
en_US |
dc.title |
Sensing technologies for detection of acetone in human breath for diabetes diagnosis and monitoring |
en_US |
dc.type |
Article |
en_US |
dc.identifier.apacitation |
Saasa, V. R., Malwela, T., Beukes, M., Mokgotho, M., Liu, C., & Mwakikunga, B. W. (2018). Sensing technologies for detection of acetone in human breath for diabetes diagnosis and monitoring. http://hdl.handle.net/10204/10591 |
en_ZA |
dc.identifier.chicagocitation |
Saasa, Valentine R, Thomas Malwela, M Beukes, M Mokgotho, CP Liu, and Bonex W Mwakikunga "Sensing technologies for detection of acetone in human breath for diabetes diagnosis and monitoring." (2018) http://hdl.handle.net/10204/10591 |
en_ZA |
dc.identifier.vancouvercitation |
Saasa VR, Malwela T, Beukes M, Mokgotho M, Liu C, Mwakikunga BW. Sensing technologies for detection of acetone in human breath for diabetes diagnosis and monitoring. 2018; http://hdl.handle.net/10204/10591. |
en_ZA |
dc.identifier.ris |
TY - Article
AU - Saasa, Valentine R
AU - Malwela, Thomas
AU - Beukes, M
AU - Mokgotho, M
AU - Liu, CP
AU - Mwakikunga, Bonex W
AB - The review describes the technologies used in the field of breath analysis to diagnose and monitor diabetes mellitus. Currently the diagnosis and monitoring of blood glucose and ketone bodies that are used in clinical studies involve the use of blood tests. This method entails pricking fingers for a drop of blood and placing a drop on a sensitive area of a strip which is pre-inserted into an electronic reading instrument. Furthermore, it is painful, invasive and expensive, and can be unsafe if proper handling is not undertaken. Human breath analysis offers a non-invasive and rapid method for detecting various volatile organic compounds thatare indicators for different diseases. In patients with diabetes mellitus, the body produces excess amounts of ketones such as acetoacetate, beta-hydroxybutyrate and acetone. Acetone is exhaled during respiration. The production of acetone is a result of the body metabolising fats instead of glucose to produce energy. There are various techniques that are used to analyse exhaled breath including Gas Chromatography Mass Spectrometry (GC-MS), Proton Transfer Reaction Mass Spectrometry (PTR-MS), Selected Ion Flow Tube-Mass Spectrometry (SIFT-MS), laser photoacoustic spectrometry and so on. All these techniques are not portable, therefore this review places emphasis on how nanotechnology, through semiconductor sensing nanomaterials, has the potential to help individuals living with diabetes mellitus monitor their disease with cheap and portable devices.
DA - 2018-01
DB - ResearchSpace
DP - CSIR
KW - Acetone detection
KW - Breath analysis
KW - Chemoresistive sensors
KW - Diabetes mellitus
KW - Nanomaterials
KW - Non-invasive diagnosis
LK - https://researchspace.csir.co.za
PY - 2018
SM - 2075-4418
T1 - Sensing technologies for detection of acetone in human breath for diabetes diagnosis and monitoring
TI - Sensing technologies for detection of acetone in human breath for diabetes diagnosis and monitoring
UR - http://hdl.handle.net/10204/10591
ER -
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en_ZA |